| Specific cell permeable inhibitor. Potent cell permeable and metabolically stable specific inhibitor of hSIRT1 (IC50=98nM in vivo / IC50=38nM in vitro; compared to hSIRT2: IC50=19µM and hSIRT3: IC50=48 μM) with no effect on human histone deacetylases (HDACs) class I and class II, nor NAD glycohydrolase (IC50>100 μg). Inhibits the deacetylation of p53 (IC50=1 μM). | |
| Reference Price: | $110.00 Click to Order |
| More Information: | CAS [49843-98-3] - C13H13ClN2O - Molecular Biology - Gene Expression |
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